{"id":15692,"date":"2017-08-09T23:25:36","date_gmt":"2017-08-10T02:25:36","guid":{"rendered":"https:\/\/www.tiabeth.com.br\/?p=15692"},"modified":"2017-08-09T23:29:11","modified_gmt":"2017-08-10T02:29:11","slug":"estudo-mostra-que-eficacia-e-seguranca-de-insulina-lispro-bio-similar-nao-e-inferior-a-humalog","status":"publish","type":"post","link":"https:\/\/www.tiabeth.com.br\/index.php\/2017\/08\/09\/estudo-mostra-que-eficacia-e-seguranca-de-insulina-lispro-bio-similar-nao-e-inferior-a-humalog\/","title":{"rendered":"Estudo mostra que efic\u00e1cia e seguran\u00e7a de insulina lispro bio-similar n\u00e3o \u00e9 inferior a Humalog\u00ae"},"content":{"rendered":"<figure id=\"attachment_15693\" aria-describedby=\"caption-attachment-15693\" style=\"width: 1000px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2017\/08\/sorella.jpg\"><img loading=\"lazy\" class=\"wp-image-15693 size-full\" src=\"https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2017\/08\/sorella.jpg\" alt=\"\" width=\"1000\" height=\"650\" srcset=\"https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2017\/08\/sorella.jpg 1000w, https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2017\/08\/sorella-300x195.jpg 300w, https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2017\/08\/sorella-768x499.jpg 768w, https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2017\/08\/sorella-765x496.jpg 765w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/a><figcaption id=\"caption-attachment-15693\" class=\"wp-caption-text\">A nova insulina dever\u00e1 ser produzida e distribu\u00edda pela Sanofi<\/figcaption><\/figure>\n<p>Um estudo comparando a seguran\u00e7a e efic\u00e1cia de SAR342434, uma forma biosimilar (insulina de lispro-Humalog\u00ae), encontrou-se compar\u00e1vel ao do medicamento de marca em pacientes tamb\u00e9m usando insulina glargina.<\/p>\n<p>A fase 3, estudo aleatorizado de SORELLA 1 avaliou as altera\u00e7\u00f5es na HbA1c, glicemia plasm\u00e1tica em jejum e n\u00edveis de glicose plasm\u00e1tica auto-monitorados, bem como eventos hipoglic\u00eamicos, e os resultados foram publicados no\u00a0<i>Diabetes Technology &amp; Therapeutics<\/i>\u00a0(DTT), um jornal revisado por pares de Mary Ann Liebert, Inc., editores.\u00a0O artigo est\u00e1 dispon\u00edvel gratuitamente no site da DTT at\u00e9 9 de setembro de 2017.<\/p>\n<p>Co-autores Satish Garg, da Universidade do Colorado Denver (Aurora), Karin Wernicke-Panten e Yvonne Kirchhein, Sanofi-Aventis Duetschland (Frankfurt, Alemanha), Maria Rojeski, Sanofi (Bridgewater, NJ), Suzanne Pierre, Sanofi (Paris, Fran\u00e7a), e Krystyna Jedynasty, Centrum Diabetologiczne (Vars\u00f3via, Pol\u00f4nia) colaboraram no artigo intitulado\u00a0<a href=\"http:\/\/online.liebertpub.com\/doi\/pdfplus\/10.1089\/dia.2017.0117\" target=\"_blank\" rel=\"noopener\">&#8220;Efic\u00e1cia e seguran\u00e7a de Biosimilar (SAR342434 Insulina Lispro) em adultos com diabetes tipo 1 tamb\u00e9m usando insulina Glargina &#8211; estudo SORELLA 1&#8221;.<\/a><\/p>\n<p>Ao longo do estudo principal de 6 meses e um per\u00edodo adicional de extens\u00e3o de seguran\u00e7a de 6 meses, a incid\u00eancia e preval\u00eancia de hipoglicemia, eventos adversos emergentes do tratamento e anticorpos anti-insulina n\u00e3o diferiram significativamente entre os dois grupos de tratamento.<\/p>\n<p>&#8220;Este \u00e9 o primeiro estudo de longa dura\u00e7\u00e3o da insulina de a\u00e7\u00e3o r\u00e1pida biossimilar (seguimento) (insulina lispro), avaliado por 1 ano, o que mostra claramente que a seguran\u00e7a e a efic\u00e1cia da insulina bio-similar s\u00e3o semelhantes \u00e0 insulina original&#8221;, disse o editor-chefe do DTT, Satish Garg, MD, Professor de Medicina e Pediatria na Universidade do Colorado Denver (Aurora).<\/p>\n<p>&#8220;Os custos dos produtos de insulina aumentaram, especialmente nos EUA. A disponibilidade de bio-similares reduzir\u00e1 o custo da insulina e tornar\u00e1 poss\u00edvel que mais pacientes com diabetes atinjam valores de HbA1c alvo&#8221;.<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.eurekalert.org\/pub_releases\/2017-08\/mali-bil080917.php\" target=\"_blank\" rel=\"noopener\">https:\/\/www.eurekalert.org\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Um estudo comparando a seguran\u00e7a e efic\u00e1cia de SAR342434, uma forma biosimilar (insulina de lispro-Humalog\u00ae), encontrou-se compar\u00e1vel ao do medicamento de marca em pacientes tamb\u00e9m usando insulina glargina. A fase 3, estudo aleatorizado de SORELLA 1 avaliou as altera\u00e7\u00f5es na HbA1c, glicemia plasm\u00e1tica em jejum e n\u00edveis de glicose plasm\u00e1tica auto-monitorados, bem como eventos hipoglic\u00eamicos, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":15693,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[19,199,196],"tags":[4178,28,1810,42,3075,1203,4179],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\r\n<title>Estudo mostra que efic\u00e1cia e seguran\u00e7a de insulina lispro bio-similar n\u00e3o \u00e9 inferior a Humalog\u00ae - TiaBeth.com<\/title>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/www.tiabeth.com.br\/index.php\/2017\/08\/09\/estudo-mostra-que-eficacia-e-seguranca-de-insulina-lispro-bio-similar-nao-e-inferior-a-humalog\/\" \/>\r\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"Estudo mostra que efic\u00e1cia e seguran\u00e7a de insulina lispro bio-similar n\u00e3o \u00e9 inferior a Humalog\u00ae - TiaBeth.com\" \/>\r\n<meta property=\"og:description\" content=\"Um estudo comparando a seguran\u00e7a e efic\u00e1cia de SAR342434, uma forma biosimilar (insulina de lispro-Humalog\u00ae), encontrou-se compar\u00e1vel ao do medicamento de marca em pacientes tamb\u00e9m usando insulina glargina. 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