{"id":5251,"date":"2015-11-19T18:26:29","date_gmt":"2015-11-19T21:26:29","guid":{"rendered":"https:\/\/www.tiabeth.com.br\/?p=5251"},"modified":"2019-07-18T00:39:51","modified_gmt":"2019-07-18T03:39:51","slug":"nova-pilula-de-insulina-promete-eficacia-na-terapia-contra-a-diabetes","status":"publish","type":"post","link":"https:\/\/www.tiabeth.com.br\/index.php\/2015\/11\/19\/nova-pilula-de-insulina-promete-eficacia-na-terapia-contra-a-diabetes\/","title":{"rendered":"Nova p\u00edlula de insulina promete efic\u00e1cia na terapia contra a diabetes"},"content":{"rendered":"<figure id=\"attachment_25688\" aria-describedby=\"caption-attachment-25688\" style=\"width: 1000px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" class=\"size-full wp-image-25688\" src=\"https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2015\/11\/pilula-insulina1.jpg\" alt=\"\" width=\"1000\" height=\"650\" srcset=\"https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2015\/11\/pilula-insulina1.jpg 1000w, https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2015\/11\/pilula-insulina1-300x195.jpg 300w, https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2015\/11\/pilula-insulina1-768x499.jpg 768w, https:\/\/www.tiabeth.com.br\/wp-content\/uploads\/2015\/11\/pilula-insulina1-765x496.jpg 765w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><figcaption id=\"caption-attachment-25688\" class=\"wp-caption-text\">Uma nova p\u00edlula de insulina pode, num futuro pr\u00f3ximo, ajudar pacientes a controlar melhor a diabetes.<\/figcaption><\/figure>\n<p>De acordo com os cientistas da Universidade da Calif\u00f3rnia, Santa Barbara, a nova droga pode fornecer uma dose mais eficaz e ajudar os pacientes que acham as\u00a0inje\u00e7\u00f5es desconfort\u00e1veis.<\/p>\n<p>&#8220;O fornecimento de insulina por inje\u00e7\u00e3o passa,\u00a0em primeiro lugar, atrav\u00e9s da circula\u00e7\u00e3o sangu\u00ednea perif\u00e9rica e, em seguida, para a circula\u00e7\u00e3o sangu\u00ednea no f\u00edgado&#8221;, explica Samir Mitragotri da UC, Santa B\u00e1rbara.<\/p>\n<p>Ele acrescentou que a administra\u00e7\u00e3o oral iria tomar uma rota mais direta.<\/p>\n<p>A produ\u00e7\u00e3o de um medicamento oral para entregar insulina em pacientes diab\u00e9ticos tem sido um grande desafio para os cientistas, devido \u00e0 dificuldade de se obter\u00a0a medica\u00e7\u00e3o ap\u00f3s o ambiente proteol\u00edtico do est\u00f4mago e do intestino, sem destruir a pr\u00f3pria prote\u00edna.<\/p>\n<p>A fim de resolver este\u00a0problema, os cientistas introduziram uma combina\u00e7\u00e3o de c\u00e1psulas com revestimento ent\u00e9rico e manchas de pol\u00edmero mucoadesivo carregadas com insulina para o novo comprimido.<\/p>\n<p>A combina\u00e7\u00e3o permite a p\u00edlula sobreviver aos \u00e1cidos do est\u00f4mago e entregar sua carga \u00fatil para o intestino delgado, de onde ele ir\u00e1\u00a0liberar os <em>adesivos\u00a0<\/em>que aderem \u00e0 parede intestinal e impedem que\u00a0as enzimas proteol\u00edticas alcancem a\u00a0insulina. A p\u00edlula, ent\u00e3o, utiliza um intensificador da permea\u00e7\u00e3o para depositar a insulina que pode, ent\u00e3o, passar para o sangue.<\/p>\n<p>&#8220;Este \u00e9 o primeiro passo essencial no que mostra que estes adesivos\u00a0podem fornecer insulina&#8221;, disse Mitragotri, acrescentando que devem ser submetidos a etapas adicionais de testes e melhoria antes que possa ser considerado como um tratamento vi\u00e1vel para a diabetes.<\/p>\n<p><a href=\"http:\/\/www.presstv.ir\/Detail\/2015\/11\/19\/438327\/diabetes-insulin-pill-therapy-blood-sugar\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/www.presstv.ir\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>De acordo com os cientistas da Universidade da Calif\u00f3rnia, Santa Barbara, a nova droga pode fornecer uma dose mais eficaz e ajudar os pacientes que acham as\u00a0inje\u00e7\u00f5es desconfort\u00e1veis. &#8220;O fornecimento de insulina por inje\u00e7\u00e3o passa,\u00a0em primeiro lugar, atrav\u00e9s da circula\u00e7\u00e3o sangu\u00ednea perif\u00e9rica e, em seguida, para a circula\u00e7\u00e3o sangu\u00ednea no f\u00edgado&#8221;, explica Samir Mitragotri da [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":25688,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[19,196],"tags":[28,184,42,38],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.3 - 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